Research-Backed Ingredients in Our All-in-One Dog Supplement | Complete Canine

Backed by Research: The Science Behind Our Dog Supplement Ingredients

What you feed your dog matters. That's why we did the research - so that you don't have to.

Check out our sources and please reach out with any questions in the contact form below.

Joint & Mobility Support

Glucosamine and Chondroitin Sulfate:

"Glucosamine and Chondroitin Use in Canines for Osteoarthritis: A Review"

This review discusses the limited clinical trial evidence supporting the use of glucosamine and chondroitin supplements for osteoarthritis in dogs, highlighting the need for more robust studies.

Open Veterinary Journal

Bhathal A, Spryszak M, Louizos C, Frankel G. Glucosamine and chondroitin use in canines for osteoarthritis: A review. Open Vet J. 2017;7(1):36-49. doi: 10.4314/ovj.v7i1.6. Epub 2017 Feb 24. PMID: 28331832; PMCID: PMC5356289.

Methylsulfonylmethane (MSM):

"Comparative Therapeutic Efficacy and Safety of Type-II Collagen (UC-II), Glucosamine and Chondroitin in Arthritic Dogs: Pain Evaluation by Ground Force Plate"

This study evaluates the efficacy of various supplements, including MSM, in managing pain and improving mobility in dogs with arthritis.

Journal of Animal Physiology and Animal Nutrition

Gupta RC, Canerdy TD, Lindley J, Konemann M, Minniear J, Carroll BA, Hendrick C, Goad JT, Rohde K, Doss R, Bagchi M, Bagchi D. Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. J Anim Physiol Anim Nutr (Berl). 2012 Oct;96(5):770-7. doi: 10.1111/j.1439-0396.2011.01166.x. Epub 2011 May 30. PMID: 21623931.

Gut & Digestive Health

Probiotics (Lactobacillus & Bifidobacterium strains):

"Gut Microbiota and Probiotics in Canine and Feline Welfare"

This study highlights the positive effects of probiotics on gut health, noting their potential to alleviate intestinal diseases and disorders in dogs and cats.

Journal of Applied Microbiology

Grześkowiak Ł, Endo A, Beasley S, Salminen S. Microbiota and probiotics in canine and feline welfare. Anaerobe. 2015 Aug;34:14-23. doi: 10.1016/j.anaerobe.2015.04.002. Epub 2015 Apr 8. PMID: 25863311; PMCID: PMC7111060.

Skin, Coat & Immune Support

Zinc (Chelated Form):

"Effects of Zinc and Linoleic Acid Supplementation on the Skin and Coat Quality of Dogs Receiving a Complete and Balanced Diet"

This study discusses the role of zinc in maintaining skin integrity, immune function, and coat quality in dogs. Chelated zinc showed better bioavailability than inorganic forms.

Veterinary Dermatology Journal

Marsh, K.A. & Ruedisueli, F.L. & Coe, S.L. & Watson, T.G.D.. (2008). Effects of zinc and linoleic acid supplementation on the skin and coat quality of dogs receiving a complete and balanced diet. Veterinary Dermatology. 11. 277 - 284. 10.1046/j.1365-3164.2000.00202.x.

Curcumin (Turmeric Extract with Piperine):

"Curcumin: A Review of Its' Effects on Human Health"

While this review focuses on human health, it provides insights into curcumin's anti-inflammatory and antioxidant properties, which are relevant to canine health.

Foods Journal

Hewlings SJ, Kalman DS. Curcumin: A Review of Its Effects on Human Health. Foods. 2017 Oct 22;6(10):92. doi: 10.3390/foods6100092. PMID: 29065496; PMCID: PMC5664031.

Heart, Brain & Longevity Support

Coenzyme Q10 (Ubiquinol Form):

"Coenzyme Q10: Clinical Applications in Cardiovascular Disease"

This review discusses CoQ10's effects on heart function, highlighting its potential benefits in managing cardiovascular diseases.

BioFactors Journal

Testai L, Martelli A, Flori L, Cicero AFG, Colletti A. Coenzyme Q10: Clinical Applications beyond Cardiovascular Diseases. Nutrients. 2021 May 17;13(5):1697. doi: 10.3390/nu13051697. PMID: 34067632; PMCID: PMC8156424.

Omega-3 Fatty Acids (DHA & EPA from Fish Oil):

"Evaluation of the Effects of Dietary Supplementation with Fish Oil Omega-3 Fatty Acids on Weight Bearing in Dogs with Osteoarthritis"

This study demonstrated that supplementation with omega-3 fatty acids from fish oil improved weight-bearing capacity in dogs with osteoarthritis, indicating benefits for joint health.

Journal of the American Veterinary Medical Association

Roush JK, Cross AR, Renberg WC, Dodd CE, Sixby KA, Fritsch DA, Allen TA, Jewell DE, Richardson DC, Leventhal PS, Hahn KA. Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. J Am Vet Med Assoc. 2010 Jan 1;236(1):67-73. doi: 10.2460/javma.236.1.67. PMID: 20043801.

Disclaimer

Please note that while some studies directly pertain to the ingredients listed, others provide broader insights into their potential benefits. It's essential to consult with a veterinarian before introducing new supplements to ensure they align with your dog's specific health needs.

NaN -Infinity
Get My Dog's Plan
Read Our Research

The Recipe

Base Carrier & Antioxidants

Absorption

  • Wild-Caught Fish Oil (Salmon, Sardine, Anchovy Blend) – A natural source of EPA & DHA Omega-3s for brain, heart, joint, and skin health.
  • Vitamin E (Mixed Tocopherols) – A powerful antioxidant that protects cells from oxidative stress and enhances skin and coat quality.
  • Rosemary Extract – A natural preservative that protects the formula from oxidation while offering mild anti-inflammatory benefits.

Joint & Mobility Support

Movement

  • Glucosamine Sulfate – Helps maintain joint structure and lubrication, reducing stiffness.
  • Chondroitin Sulfate – Supports cartilage elasticity and shock absorption in joints.
  • MSM (Methylsulfonylmethane) – A natural compound that reduces inflammation and improves joint flexibility.
  • Magnesium – Supports muscle and nerve function while playing a key role in bone health.

Gut Health

Digestion

  • Probiotics (Lactobacillus & Bifidobacterium strains) – Improves digestion, balances gut bacteria, and enhances immune function.
  • Pumpkin Seed Oil – Supports gut health and digestion while reducing inflammation and promoting a healthy coat.

Skin, Coat & Immune Support

Glow

  • Zinc (Chelated) – An essential mineral that boosts skin health, immune defense, and wound healing.
  • Biotin – Promotes healthy skin and a shinier, stronger coat.
  • Vitamin D3 – Supports bone health, immune function, and calcium absorption.
  • Curcumin (Turmeric Extract) – A natural anti-inflammatory ingredient that supports joint health, digestion, and immune resilience (microencapsulated for maximum absorption).

Heart, Brain & Longevity Support

Vitality

  • CoQ10 (Ubiquinol form) – A potent antioxidant that supports heart health, energy production, and cognitive function.
  • DHA & EPA (from Fish Oil) – Essential fatty acids that support brain function, cardiovascular health, and anti-inflammatory responses.
Get My Dog's Plan